Ashley Brower Niesman CV

Ashley Brower Niesman

2023-present — Senior Research Associate and Lab Manager, Department of Biophysics, UT Southwestern Medical Center
2013-present — Senior Research Associate and Lab Manager, Department of Pharmacology, UT Southwestern Medical Center
2012-2013 — Research Assistant II and Lab Manager, Department of Pharmacology, UT Southwestern Medical Center
2008-2012 — Laboratory Supervisor, Marymount Manhattan College
2006-2007 — Research Intern, Memorial Sloan Kettering Cancer Center

Fung HYJ, Jiou J, Niesman AB, Bernardes NE, Chook YM. Nap1 and Kap114 co-chaperone H2A-H2B and facilitate targeted histone release in the nucleus. J Cell Biol. 2025 Jan 6;224(1):e202408193.
Hudman-Wing CE, Fung HYJ, Cagatay T, Kwanten B, Niesman AB, Gharghabi M, Permentier B, Shakya B, Shacham S, Landesman Y, Lapalombella R, Daelemans D, Chook YM. Allosteric degraders induce CRL5 ASB8 mediated degradation of XPO1. bioRxiv [Preprint]. 2024 Oct 11:2024.10.07.617049.
Fung HYJ, Mittal SR, Niesman AB, Jiou J, Shakya B, Yoshizawa T, Cansizoglu AE, Rout MP, Chook YM. Phosphate-dependent nuclear export via a novel NES class recognized by exportin Msn5. bioRxiv [Preprint]. 2024 Aug 12:2024.08.12.607649.
Fung HYJ, Niesman A, Chook YM. An update to the CRM1 cargo/NES database NESdb. Mol Biol Cell. 2021 Mar 15;32(6):467-469.
Gonzalez A, Mannen T, Çağatay T, Fujiwara A, Matsumura H, Niesman AB, Brautigam CA, Chook YM, Yoshizawa T. Mechanism of karyopherin-β2 binding and nuclear import of ALS variants FUS(P525L) and FUS(R495X). Sci Rep. 2021 Feb 12;11(1):3754.
Volpon, L., Culjkovic-Kraljacic, B., Osborne, M. J., Ramteke, A., Sun, Q., Niesman, A., Chook, Y. M., & Borden, K. L. (2016). Importin 8 mediates m7G cap-sensitive nuclear import of the eukaryotic translation initiation factor eIF4E. Proceedings of the National Academy of Sciences of the United States of America, 113(19), 5263–5268.

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